The most anticipated game of the week is unquestionably at the Emirates where third-placed Arsenal entertain second-placed Manchester City. Following an impressive win over Birmingham, the hosts can overtake their opponents with a win but that will not be an easy task as City boast the best away record in the League while Arsenal have a poor home record for their standards.
The Emirates plays host to Arsenal versus Manchester City in a crucial clash at the top-of-the-table
Chelsea, who sit 16th in the form table after dropping more points against Aston Villa on Sunday, travel to bottom-of-the-table Wolves and the most in-form team in the league, Tottenham, visit Everton looking to record their fourth straight win.
Teams in the relegation zone, Birmingham and Fulham, play Blackpool and West Brom respectively and fellow strugglers face a trip to Bolton.
This week will again be an important stage in who will finish where at either ends if the table.
Premier League 2010/11 stats